As preparations continue for Meredith and Derek’s wedding, Izzie receives a surprise hospital visit from her handful-of-a-mother, Robbie. Meanwhile, a newly sober Thatcher visits his daughters, Meredith and Lexie, in…

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation…

In the first part of the two hour season finale, Izzie spends time with a fellow cancer patient and contemplates whether or not to undergo a risky surgery, as Mark…

In the second part of the two hour season finale, George delivers stunning news to Bailey, sending shockwaves throughout the hospital, and Izzie’s friends anxiously await her recovery from surgery….

Now that Derek has the engagement ring, he searches for the perfect way to propose to Meredith, as Lexie demands that Mark go public with their relationship, and Bailey, encouraged…

Addison, Naomi and Sam rush the ailing Archer to Seattle Grace and reunite with old friends Derek and Mark to help save his life; meanwhile, Izzie employs her fellow doctors…

Derek’s confidence is shaken like never before as he faces off with Addison over what course is best for their dying pregnant patient; Cristina calls the abilities of a renown…

Derek decides to quit after learning that more of his patients have died than survived; Izzie’s interns make an unsettling discovery about “Patient X.”

After his fellow surgeons try and fail to bring Derek back to work, Meredith must summon the strength to convince him. Meanwhile the hospital is abuzz as Mark attempts a…

All eyes are on Derek as he is set to perform his first surgery after his breakdown; attention is also set on Izzie, whose medical condition requires her to undergo…

As she endures aggressive treatment for her cancer, Izzie throws herself into planning Derek and Meredith’s wedding.

Derek’s mother, Carolyn, makes a surprise visit to Seattle and meets Meredith for the first time, as Mark tries to conceal his relationship with Lexie from her as well; meanwhile,…

Bailey grows desperate as a patient’s condition becomes more and more dire. Everyone in the hospital is stepping up to try to find the boy a new organ donor, including…

Meredith, Cristina and Bailey come to Lexie and Sadie’s rescue when a routine surgery goes horribly wrong, as Owen and Derek treat a man seriously injured while sleepwalking and Mark…

Cristina is awarded the first solo surgery among the residents, but she is forced to give it up and choose her replacement; Lexie is impressed when Mark performs a cutting-edge…

Bailey teams with Seattle Grace’s new pediatric surgeon, Dr. Arizona Robbins, to save the life of a young patient near and dear to her heart, as the admittance of a…

As Meredith and Derek begin to find that their “happily ever after” is anything but easy, Cristina develops a crush on a military doctor who brings in a trauma patient….

Alex is offended when Izzie talks about how great a man Alex is to Meredith. Derek is stabbed with the scalpel in the palm of his hand by Rose, while…

When the plumbing springs a leak, chaos breaks out at Seattle Grace as the Chief tries to put in place new teaching methods. Meanwhile, George takes his residency exam; and…

Meredith is sent into a state of panic when Derek finds her mother’s diary in the house. Meanwhile, Callie stresses while preparing for her first date with Erica. Later, Cristina…

Bailey heads up a “domino procedure” in which each surgery hinges on the one preceding it. Meanwhile, Derek gets sole credit for the brain-tumor study he did with Meredith; Lexie…

The chief gives Bailey new power and responsibility. He also gives her a very difficult surgical assignment: remove a girl’s inoperable tumor. Meanwhile, new trauma chief Owen (Kevin McKidd) challenges…

When the Chief makes an announcement that a solo surgery is up as an award, the residents are sent into a frenzy all trying to get an edge over one…

One of Meredith’s oldest friends, Sadie, becomes an intern at Seattle Grace, but Mer’s friends are less-than-welcoming to her.