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Everyone pulls together to help Callie and baby Sofia on their painstaking journeys to recovery in hopes of allowing mother and baby to finally meet; the sudden death of a…

As Callie and Arizona’s wedding approaches, the couple quickly realize that the day they’ve been looking forward to is not turning out the way they’d envisioned. Meanwhile Alex continues to…

Personal and work pressures are adding up and have Meredith visibly on edge, Owen conducts formal interviews for the Chief Resident position, Cristina grows increasingly defiant, Alex and Lucy’s undefined…

News of Meredith’s dishonesty in the clinical trial comes to light, leading to unanticipated consequences for her and others; Cristina finds herself in a compromising situation, which forces her to…

Derek breaks ground on his Alzheimer’s clinical trial and Meredith can’t help but feel left out; Bailey’s attempt to take the hospital into the age of new media with live…

Thatcher Grey, Meredith and Lexie’s father, returns to Seattle Grace with stomach pains and a new, twenty-something tattooed girlfriend, Danielle. Meanwhile, Alex clashes with the new OB, Dr. Lucy Fields,…

Meredith, looking to prove she is Chief Resident material, learns that anything and everything can happen in an hour’s time when she steps up to run the ER for a…

Meredith must choose between her fertility treatments and her eyesight when she begins having trouble seeing, Mark makes it clear to Callie and Arizona that he takes his role as…

Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer’s trial, but will Adele stand in her own way? Meanwhile Mark and Arizona have conflicting ideas of…

A cataclysmic event leaves the doctors shaken; Callie, on the verge of a life-changing moment, starts imagining about the hospital and her friends.

The residents are on their own with the dreaded night shifts while the attendings go out to play to celebrate Derek’s grant for his clinical trial.

Derek takes Cristina out on a fishing trip; Teddy tries to help a patient who lacks the proper insurance to seek medical treatment.

A gunman opens fire at a local college, sending mass casualties to the hospital; Arizona’s return is not warmly received.

Arizona tries to reconcile with Callie, who has big news to share; Teddy faces an important decision; the residents receive new interns; the Chief makes an announcement.

A documentary crew visits the hospital six months after the shooting to document the road to recovery for doctors and patients; Meredith helps Cristina put on a brave face for…

Owen puts the residents through a rigorous trauma certification drill; Cristina is left alone to monitor an ill lung transplant patient.

A team of doctors tries to save the life of a political figure from the Middle East; Cristina decides to decorate her new place and throw a housewarming party; Alex…

In the wake of the shooting at Seattle Grace-Mercy West, the doctors find themselves in a frenzy: Christina and Owen will be getting married, and others are trying to deal…

Meredith finally tells Derek about her pregnancy and miscarriage; during a surgery, Cristina experiences PTSD; Bailey won’t let Alex operate until he has the bullet in his chest removed.

Issues surface when Derek’s estranged sister, Amelia (Caterina Scorsone), visits unexpectedly; Meredith and Derek continue to try to ease Cristina back into surgery.

Derek and Meredith visit the obstetrician and receive disturbing news; Lexie notices April and Meredith growing closer; Jackson tries to get ahead in the operating room.

As part of their training, Seattle Grace’s residents are put in charge; the attending surgeons compete for a million-dollar grant.